G4185
From £27.13 GBP
Product Description
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Product Documentation
Product Description

C20H40N4O10.2H2SO4=692.7

G-418 is a member of the large family of Aminoglycoside antibiotics and has a molecular structure almost like Gentamycin. The antibiotic is an irreversible inhibitor of protein synthesis. Due to its structure is capable of binding to both prokaryotic and eukaryotic ribosomes and inhibiting protein synthesis and generating errors in the transcription of the genetic code.

G-418 can by inactivated by NPTII or 3APH. The hydroxyl group present at the 3 position of G-418 is phosphorylated by NPTII. The resulting steriometric change of the molecular structure of the antibiotic prevents it from binding at its ribosome binding site.

Specifications

 
Character Fine white powder
Solubility Freely soluble in water
Specific Optical Rotation 104 ~ 121
Water <6%
Absorbance 570 nm <0.10
Absorbance 280 nm <0.015
NH4 < 1.0%
pH  5.5 0.5
Thin Layer Chromatogram One Spot
Potency >720 µ/mg

Store at 2 - 8°C 

Protect from light

CAS 108321-42-2   

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Product Documentation
Size: 5g
  • 5g
  • 1g
Quantity
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Yes – custom dry powder media is one of our core specialisms. Whether you're standardising an internally developed culture or need to create something entirely new, we will work with you to create a bespoke solution.
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We aim to dispatch standard orders within 2 to 4 working days. For custom formulations, lead times vary depending on complexity – we’ll confirm timings during the quote process.
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University of Dundee
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“Formedium has been a long-term supplier of media products to our fermentation facility. From day one, their product quality and customer service has been second to none. Impressively, their outstanding service has always been delivered alongside competitive pricing and a sense of that personal touch. Formedium have even formulated and packaged media, specifically for our needs, and their technical support has always been on hand when needed.”
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