Knowledge
Complete Supplement Mixture (CSM) Drop-Outs
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Complete Supplement Mixture (CSM) is a combination of Amino Acids, Vitamins and other essential components to support a vigorous growth of cells in CSM supplemented medium. Yeast Nitrogen Base media without Amino Acids supplemented with CSM have been proven to be an excellent combination for the cultivation of almost all strains of Saccharomyces Cerevisiae and to supplement encountered auxothrophies.
CSM is also a basis for many “Drop-Out” mixtures to select for auxotrophic requirements and transformants. 
Each CSM Drop-Out mixture contain all components except for one to five essential nutrients, i.e. the “dropped out” supplements. Some CSM Drop-Out mixtures are also available with additions of extra Amino Acids and other components.
Complete Supplement Mixture formulations are available in 10 gram and 100 gram pack sizes. If you would like to order, or get a quote, on a larger pack size, please  contact us.
Please enquire about  custom made formulations.
Why choose Formedium?
Bespoke culture 
solutions
Whether you’re using industry standard media or producing your own formulation, our technical team works closely with you to deliver a consistent, reliable and cost-effective solution.
Fast, reliable

fulfilment
With UK-based production, global distribution and streamlined processes, we’re able to respond quickly to urgent timelines without compromising on quality.
Certified 
Quality
We hold ISO 9001 certification and have ISO 14001 environmental accreditation. Every batch of powdered media and every ingredient is fully traceable.
Environmental 
responsibility
We take sustainability seriously – from solar panels and rainwater collection at our facility to recyclable packaging and responsible procurement.
Testimonials
What our customers say
"Formedium provide not only excellent products but also a level of personal service that truly sets them apart. They take the time to understand their customers’ needs and consistently go above and beyond, all while maintaining a highly professional approach. I look forward to continuing to work with Formedium and the team for many years to come."
Michael Hannan
University of Dundee
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“Formedium's technical support assisted us to make ready-made Aspergillus medium, saving us countless hours in preparation and have consistency across experiments going forwards. Their cost-effectiveness impressed us so much that we've now switched all our medium consumables to them!”


Norman Van Rhijn
University of Manchester
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“Formedium has been a long-term supplier of media products to our fermentation facility. From day one, their product quality and customer service has been second to none. Impressively, their outstanding service has always been delivered alongside competitive pricing and a sense of that personal touch. Formedium have even formulated and packaged media, specifically for our needs, and their technical support has always been on hand when needed.”
Dr Shane Palmer
Cambridge Biomedical Campus
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